What ultimately happens as a result of complement activation?

Study for the University of Central Florida PCB3233 Immunology Exam. Engage with flashcards and multiple choice questions, each complete with hints and explanations. Prepare effectively for your exam!

The correct choice indicates that the ultimate result of complement activation is the death of pathogens. Complement activation is a crucial part of the innate immune response and involves a series of proteins that work together to identify and eliminate invading microorganisms. This process enhances the efficiency of the immune response through various mechanisms.

When the complement system is activated, it leads to the formation of the membrane attack complex (MAC), which creates pores in the membranes of pathogens such as bacteria. This results in lysis of the pathogen, effectively killing it. Additionally, complement proteins can opsonize pathogens, marking them for destruction by phagocytes, further assisting in the elimination of infectious agents.

The other options are less relevant as consequences of complement activation. Inhibition of adaptive immunity is not an action associated with complement, and indeed complement can enhance the adaptive immune response by promoting antigen presentation. Chronic inflammation is a separate process that may involve many different signals and pathways, and while complement activation can contribute to inflammation, it is not the primary result. Lastly, enhancement of cell proliferation does not directly relate to the function of the complement system, as its primary role is to target and eliminate pathogens rather than stimulate cell division.

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