What type of cells have receptors for both C3b and iC3b?

Phagocytic cells possess receptors for both C3b and iC3b, which are crucial components of the immune response. C3b is a fragment of the complement system that opsonizes pathogens, making them more recognizable and easier to engulf by phagocytes. The presence of C3b on pathogens enhances their uptake by phagocytic cells through receptors like CR1 (Complement Receptor 1) that bind to C3b.

iC3b, which is another product of complement activation, also serves as an opsonin but in a slightly different form. Phagocytes have receptors for iC3b, such as CR3 and CR4, which facilitate the recognition and subsequent phagocytosis of iC3b-coated targets. The ability of phagocytic cells to engage both C3b and iC3b ensures a robust response to pathogens, leading to their effective clearance from the body.

The other cell types listed do not have the same complement receptor profile or the primary role in phagocytosis. Natural killer cells are primarily involved in the destruction of virally infected cells and tumor cells but do not utilize C3b or iC3b for their cytotoxic functions. Helper